The 15-year-old Florida girl whose continuous hiccups got her international attention seems to be in trouble again. Jennifer Mee, who started hiccupping on Jan. 23 close to 50 times a minute and continued through for more than a month, began hiccupping again Thursday morning after a nose bleed that occurred during her second day back at school.

"I'm at my wit's end," the girl's mother, Rachel Robidoux, told the St. Petersburg Times.

Robidoux said her daughter was really happy to be back at school with friends but the recurrence of hiccups has left her upset, discouraged and in pain.

After 37-days of continuous hiccups, which stopped only during her sleep, Jennifer was taken to the emergency room earlier this month. They stopped and Mae felt it was safe to go back to school.

During her first bout of hiccups, Jennifer tried a number of approaches to ease her symptoms including home remedies, treatment and advices from an infectious disease specialist, a neurologist, a chiropractor, an acupuncturist and even a hypnotist.

A patented device designed to stop hiccups, also failed to help the girl, according to the Associated Press reports.

According to the National Institute of Health, hiccups are caused by involuntary contractions of the diaphragm, which causes the vocal cords to close briefly, making that distinctive sound. They can be triggered by anything from spicy foods to stress.