CHF is considered to be a life threatening and serious illness, which results in premature death. If the heart is assumed as a pump, then progressive damaged cause to its muscle fibers may result in reduced ‘efficiency’, causing blood to backup under pressure within vascular system. Swelling is caused in the whole body (edema) due to increased back pressure, specifically in the lungs, lower extremities, liver and the heart. In severe cases, CHF is said to be associated with profound breath shortness and generalized weakness.
Millions of people across the globe are said to suffer from CHF and more new cases are being diagnosed every year. Even though CHF related mortality deaths have improved drastically in the last few decades, the death rate that is associated with CHF is found to be 50%. With population the world over growing older, CHF incidence is only expected to rise further. The famous doctors for bone marrow transplant in India can provide the best possible treatment and assure quick recovery.
Several risks are associated with CHF which includes myocardial infarction (heart attack), coronary artery disease, diabetes, hypertension (high blood pressure), elevated cholesterol, smoking and diseased heart valves. The leading causes for CHF in majority of the countries are myocardial infarction and coronary artery disease.
Understanding the Issue and Providing Treatment
Heart muscle fibers or cardiac myocytes as they are known in adults which has got damaged due to myocardial ischemia (chronic oxygen deprivation) or myocardial infarction (oxygen loss) are not in a position to regenerate themselves. Scar tissue which interferes with pumping action of the heart is replaced with scar tissue.
Clinical management with regards to heart injury caused by infarction or ischemia includes usage of medications like ACE inhibitors, aspirin, nitrates, aldosterone antagonists and beta-blockers. The ‘reperfusion strategies’, which includes CABG (coronary artery bypass graft) surgery and coronary artery stent placement will be required in few patients. As the blood pumping muscle fibers of the heart becomes replaced extensively with fibrosis (non-contractile scar tissue), there is development of irreversible CHF. At this particular point only symptomatic management will be possible. The best bone marrow transplant specialist in India will make sure that they provide the very best support and treatment to their patients, helping them to recover soon from their ailment.
Clinical studies have been conducted in humans and animals to understand stem cell auto transplantation use in the hearts that are damaged due to CHF. Even though reproduction or regeneration is not possible in mature cardiac myocytes following infarction or ischemia, the primitive ‘pluropotential’ stem cells present within the bone marrow are presumed to be capable to differentiate or metamorphose into any specialized body cell type, including cardiac myocytes. But, this kind of transformation to specialized and differentiated cardiac muscle cell from undifferentiated stem cell of bone marrow is said not to take place naturally in human body.
The Indian physicians are well versed with the treatment procedures and are ready to take up all challenges faced by them to provide respite to the patients.